Drug therapy

Nonsteroidal anti-inflammatory drugs (NSAIDs) should be avoided after bariatric surgery because of the risk of gastric and marginal ulcer development. In many bariatric centers, proton pump inhibitor therapy is prescribed postoperatively, as evidence from cohort studies suggests that it may decrease ulcer risk. Endocrinologists and primary care providers should be prepared to adjust the dose of any medication that is dosed based on weight (e.g., levothyroxine), and to consider potential effects of malabsorption on a patient’s usual oral medications.In some cases, patients may need increased dosages of a drug to receive the same effect. In addition, some non-steroidal, anti-inflammatory drugs (Aspirin and NSAIDs) can cause ulcers or stomach irritation in patients who have undergone gastric bypass.

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